The Lakers, ranked No. 1 in the Super 25, shot 51 percent from the field and had five players in double figures. La Lumiere has scored at least 89 points in its last four games.
Isaiah Coleman-Lands had 21 points, Jordan Poole had 20, Brian Bowen had 16, Jaren Jackson had 14 (along with 10 rebounds) and Jacob Epperson had 10. Tyger Campbell finished with 16 assists.
The game was tied at 10-10, but La Lu led 41-25 at halftime before pushing the margin to 47 late in the game.
La Lumiere faces No. 13 New Albany on Thursday, although the Bulldogs are likely to fall in the rankings after an 84-60 loss Saturday to North Central in the Tip Off Classic at Southport Fieldhouse in Indianapolis.